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. 2014 Mar 20;8:25. doi: 10.3389/fncir.2014.00025

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Copyright © 2014 Lou, Luo, Zhang, Tao, Chen, Zhou and Xiong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The shortened EPSP was caused by VTA activation rather than the adaptation to repeated sound simulation. (A) An example of neuronal responses to three stimulation groups: sound only, paired VTA-sound, sound only (again, after paired VTA-sound). Superimposed traces of 5 repetitions. Scale bar: 5 mv/10ms. (B) When sound-only stimulation were delivered again the duration of evoked response in A1 neuron was not significantly different from the duration when sound-only stimulation was first applied (*p < 0.05; **p < 0.01, paired t-test; filled triangle: sound-only stimulation; filled square: paired VTA-sound stimulation; filled circle: sound-only stimulation that was delivered again after paired VTA-sound stimulation).