Table 2. Cox proportinal hazards model of prognostic factors in patients with pancreatic cancer (n=48).
| |
Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| Factor | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age (⩾60 years) |
0.934 |
0.418–2.084 |
0.867 |
NA |
NA |
NA |
| Gender (male) |
0.885 |
0.415–1.887 |
0.752 |
NA |
NA |
NA |
| T factor (T4) |
1.433 |
0.642–3.199 |
0.380 |
NA |
NA |
NA |
| Tumour size (⩾40 mm) |
2.166 |
1.010–4.646 |
0.047 |
1.738 |
0.748–4.042 |
0.199 |
| Lymph-node status (positive) |
6.712 |
1.585–28.421 |
0.010 |
5.620 |
1.312–24.071 |
0.020 |
| Vascular invasion (positive) |
1.768 |
0.769–4.068 |
0.180 |
NA |
NA |
NA |
| Perineural invasion (positive) |
1.726 |
0.797–3.740 |
0.166 |
NA |
NA |
NA |
| Resection margin (positive) |
5.757 |
2.501–13.251 |
<0.001 |
5.394 |
2.227–13.068 |
<0.001 |
| Microvessel densitya (⩾25) |
1.214 |
0.543–2.715 |
0.637 |
NA |
NA |
NA |
| Neuropilin-1 expression (high) | 2.334 | 1.072–5.083 | 0.033 | 2.391 | 1.045–5.469 | 0.039 |
Abbreviations: CI=confidence interval; HR=hazard ratio; NA=not applicable.
a
Number of vessels per 100 magnification field.