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. Author manuscript; available in PMC: 2014 Mar 20.
Published in final edited form as: Nat Genet. 2014 Jan 12;46(2):116–125. doi: 10.1038/ng.2874

Figure 6. Acquired somatic events in ETV6-RUNX1 ALL.

Figure 6

(A) Each column represents a sample. The first row indicates the patients with exome sequencing data, the second row depicts samples with whole-genome sequencing data for rearrangements. In the ETV6-RUNX1 row, purple boxes indicate the automated detection of the fusion genes in the samples that whole-genome sequencing was performed. First panel concentrates on genes that are predominantly affected by genomic rearrangement. Second panel annotates previously characterized cancer genes that are recurrently mutated in the present study. Crosses indicate homozygote events and mixed colors indicate occurrence of more than one type of event in the same sample. (B) Independent deletion of ATF7IP. Copy number plot showing a focal deletion of ATF7IP in PD4028a, RgID HS20_6248:31106.