Figure 3.

Effect of pPVT lesions on freezing to fear-conditioning tones. (A) Different experimental groups displayed similar amounts of freezing prior to electrolytic lesions of the pPVT. In contrast, freezing was attenuated in groups of rats that had pPVT and midline lesions when they were compared to the control lesion group. Data points are represented as percent freezing over the first three tone presentations (first test block). (B) The different groups showed similar extinction of freezing behavior over subsequent presentations of the tone. Each data point represents percent freezing for three consecutive tone presentations (one test block) with the first data point representing the same data as in Figure 2A. (C) Lesions of the pPVT or the midline thalamus had no effect on recall of the extinguished fear memory as measure by percent freezing over three tone presentations. *p < 0.05; **p < 0.01. Results are presented as mean ± SEM.