Table 4.
Proteins that had at least a 2-fold higher expression in alveolar macrophages from men.
| Spot number |
Mean of normalized volume of male |
Mean of normalized volume of female |
Fold changes (male/female) |
Accession number (Swiss-Prot) |
Protein ID | Mowse score |
Observed pI/Mr (KDr) |
Number of peptides by MS/MS |
Total seq. coverage (%) |
|---|---|---|---|---|---|---|---|---|---|
| 867 | 0.04867 | 0.02083 | 2.34 | NP_006079 | Tubulin, beta, 2 | 2103 | 5.0/53.3 | 8 | 62 |
| 1009 | 0.05650 | 0.02167 | 2.61 | BAD96752 | Beta-actin variant | 471 | 7.5/45.1 | 8 | 31 |
| 1318 | 0.12600 | 0.02983 | 4.22 | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 427 | 6.2/39.6 | 4 | 39 |
| 1773 | 0.22083 | 0.06217 | 3.55 | NP_001900 | Cathepsin D preproprotein | 898 | 5.2/27.7 | 5 | 33 |
| 1802 | 0.06200 | 0.03067 | 2.02 | P30041 | Peroxiredoxin 6 | 364 | 6.0/27.4 | 7 | 76 |
| 1872 | 0.05017 | 0.01600 | 3.14 | P25787 | Proteasome subunit alpha type 2 | 265 | 6.6/25.7 | 6 | 76 |
| 3074 | 0.17217 | 0.07350 | 2.34 | 1IVY_A | Chain A, Physiological Dimer Hpp Precursor | 230 | 4.5/29.4 | 3 | 9 |
| 3157 | 0.06600 | 0.03250 | 2.03 | P05092 | Cyclophilin A | 206 | 6.4/16.4 | 3 | 52 |
| 3235 | 0.11967 | 0.01050 | 11.40 | P11021 | 78 kDa glucose-regulated protein | 2193 | 5.3/74.9 | 24 | 50 |
| 4880 | 0.09550 | 0.00567 | 16.85 | CAA68491 | Glutathione peroxidase | 1143 | 5.5/23.6 | 4 | 89 |
| 4925 | 0.12867 | 0.00100 | 128.67 | P26447 | Protein S100-A4 | 208 | 5.9/11.9 | 5 | 45 |
| 4990 | 0.11867 | 0.01933 | 6.14 | P00558 | Phosphoglycerate kinase 1 | 2011 | 7.9/44.9 | 13 | 72 |
| 5173 | 0.11133 | 0.03450 | 3.23 | P30048 | Thioredoxin-dependent peroxide reductase, mitochondrial | 204 | 7.7/28.0 | 3 | 16 |
| 5180 | 0.10050 | 0.03300 | 3.05 | Q06830 | Peroxiredoxin-1 | 636 | 7.3/22.2 | 7 | 47 |
| 8849 | 0.06850 | 0.00100 | 68.50 | P54727 | UV excision repair protein RAD23 homolog B | 643 | 4.8/43.2 | 8 | 41 |
| 8872 | 0.05933 | 0.02533 | 2.34 | P06576 | ATP synthase subunit beta, mitochondrial | 513 | 5.3/56.5 | 8 | 34 |
| 8985 | 0.09233 | 0.01900 | 4.86 | P06733 | Enolase 1 | 638 | 5.7/42.3 | 8 | 28 |
| 9003 | 0.15800 | 0.03033 | 5.21 | AAA51580 | Gamma-actin | 620 | 4.6/43.3 | 3 | 19 |
| 9023 | 0.63483 | 0.28000 | 2.27 | Q3ZCM7 | Tubulin beta-8 chain | 344 | 4.8/49.7 | 4 | 18 |
| 9103 | 0.05133 | 0.01850 | 2.77 | P06396 | Gelsolin | 1241 | 5.9/85.6 | 4 | 25 |
| 9126 | 0.06717 | 0.01100 | 6.11 | O95336 | 6-phosphogluconolactonase | 331 | 5.7/27.8 | 4 | 39 |
| 9141 | 0.10867 | 0.03400 | 3.20 | 1HJO_A | Chain A, Heat-Shock 70 kd Protein 42 kd Atpase N-Terminal Domain | 1329 | 7.4/28.6 | 5 | 45 |
| 9152 | 0.08583 | 0.00217 | 39.62 | P09668 | Procathepsin H | 517 | 8.4/37.4 | 3 | 29 |
| 9153 | 0.13433 | 0.01400 | 9.60 | P52566 | Rho GDP-dissociation inhibitor 2 | 616 | 5.1/23.0 | 10 | 75 |
| 9169 | 0.09733 | 0.04633 | 2.10 | AAA35607 | IgE-binding protein | 257 | 7.4/26.1 | 2 | 22 |
| 9337 | 0.10317 | 0.04183 | 2.47 | 1GLO_A | Chain A, Crystal Structure Of Cys25ser Mutant Of Human Cathepsin S | 193 | 6.6/16.5 | 5 | 32 |
| 9408 | 0.29833 | 0.12683 | 2.35 | 1AWI_A | Chain A, Human Platelet Profilin complexed with The L-Pro10 Peptide | 988 | 9.1/14.5 | 2 | 93 |
| 9504 | 2.49950 | 1.10067 | 2.27 | P08670 | Vimentin | 2541 | 5.1/53.6 | 12 | 63 |
| 9734 | 0.11817 | 0.00100 | 118.17 | P10809 | 60 kDa heat shock protein, mitochondrial | 2283 | 5.7/61.0 | 13 | 56 |
Only identified proteins are shown. Accession number: international database of the name and ID number of protein. Fold change: average density of the specific protein in males compared to females. Mowse score: measures reliability of the protein identification; greater than 100 ensures higher reliability that the protein identified is correct. Observed pI/Mr: isoelectric point and molecular weight of the protein. Ms/Ms: number of peptides sequenced after digestion. Total sequence coverage: percentage of the peptide sequenced.