Table 5.
Proteins that had at least a 2-fold higher expression in alveolar macrophages from women.
Spot number |
Mean of normalized volume of male |
Mean of normalized volume of female |
Fold changes (female/male) |
Accession number (Swiss-Prot) |
Protein ID | Mowse score |
Observed pI/Mr (KDr) |
Number of peptides by MS/MS |
Total seq. coverage (%) |
---|---|---|---|---|---|---|---|---|---|
778 | 0.0317 | 0.1257 | 3.97 | P19971 | Thymidine phosphorylase | 326 | 5.2/55.0 | 8 | 31 |
947 | 0.4037 | 0.9677 | 2.40 | O14773 | Tripeptidyl-peptidase I | 427 | 5.7/47.6 | 3 | 19 |
1526 | 0.0402 | 0.0855 | 2.13 | P07355 | Annexin A2 | 422 | 7.6/38.6 | 6 | 36 |
2342 | 0.0182 | 0.0443 | 2.44 | Q16781 | Ubiquitin-conjugating enzyme E2 N | 134 | 5.7/15.7 | 2 | 22 |
2536 | 0.0575 | 0.1312 | 2.28 | P01884 | Beta-2-microglobulin | 107 | 6.0/12.0 | 2 | 34 |
4917 | 0.2527 | 1.0122 | 4.01 | CAA23759 | Unnamed protein product | 1004 | 7.0/13.6 | 2 | 95 |
4947 | 0.0657 | 0.1440 | 2.19 | NP_004842 | Napsin A preproprotein | 1678 | 5.3/35.0 | 3 | 22 |
8844 | 0.0028 | 0.0513 | 18.12 | Q02818 | Nucleobindin-1 | 282 | 5.2/53.8 | 11 | 29 |
9158 | 0.0893 | 0.1852 | 2.07 | 1JHW_A | Chain A, Ca2+-binding mimicry in the crystal structure of the Eu3+-bound mutant human macrophage capping protein cap G | 1063 | 4.9/26.3 | 5 | 34 |
9207 | 0.0112 | 0.0510 | 4.57 | P07203 | Glutathione peroxidase | 320 | 5.5/24.2 | 4 | 54 |
9501 | 0.0447 | 0.0922 | 2.06 | P43686-2 | Proteasome 26S ATPase subunit 4 isoform 2 | 192 | 5.0/62.7 | 3 | 18 |
9629 | 0.0725 | 0.2178 | 3.00 | P07237 | Protein disulfide-isomerase | 937 | 4.8/57.1 | 8 | 34 |
9658 | 0.0245 | 0.1052 | 4.29 | P26038 | Moesin | 539 | 6.1/67.9 | 6 | 13 |
Only identified proteins are shown. Accession number: international database of the name and ID number of protein. Fold change: average density of the specific protein in males compared to females. Mowse score: measures reliability of the protein identification; greater than 100 ensures higher reliability that the protein identified is correct. Observed pI/Mr: isoelectric point and molecular weight of the protein. Ms/Ms: number of peptides sequenced after digestion. Total sequence coverage: percentage of the peptide sequenced.