Skip to main content
. 2014 Feb 3;592(Pt 6):1295–1308. doi: 10.1113/jphysiol.2013.266858

Table 3.

Effect of the duration of dopamine infusion on the ventilatory reaction to dopamine withdrawal

Change after dopamine withdrawal (%)
Measured parameter Duration of dopamine infusion (min) Subject A Subject B
Minute ventilation 15 +11 +10
60 +19 +50
Tidal volume 15 +11 −1
60 +36 +60
Breathing rate 15 +1 +19
60 −14 −7

Note that the pronounced increase in minute ventilation observed with long administration is mainly driven by an increment in tidal volume. Subject A has hypoxic ventilatory response of 0.2 l min–1/Inline graphic and subject B of 1.1 l min–1/Inline graphic.