Table 3.
Calcium sensitivity of isometric force
| Control |
Cmpt |
|||
|---|---|---|---|---|
| EDL (n = 8) | Soleus (n = 8) | EDL (n = 7) | Soleus (n = 8)# | |
| Cross section (μm2) | 1887 ± 343 | 1714 ± 235 | 2602 ± 380 | 3303 ± 386* |
| Tactive (kN m−2) | 26.14 ± 5.06 | 26.87 ± 3.98 | 25.25 ± 4.01 | 21.89 ± 2.18 |
| Tpassive (kN m−2) | 2.24 ± 0.58 | 2.07 ± 0.48 | 2.15 ± 0.47 | 2.86 ± 0.37 |
| kt (s−1) | 3.43 ± 0.39 | 1.98 ± 0.21 | 6.15 ± 0.65** | 1.84 ± 0.40 |
| pCa50 | 5.73 ± 0.02 | 5.73 ± 0.04 | 5.77 ± 0.03 | 5.78 ± 0.05 |
| nH | 3.21 ± 0.19 | 3.12 ± 0.29 | 3.15 ± 0.16 | 2.75 ± 0.20 |
**
Significant difference at P < 0.01 as compared to control.
#
Numbers in parentheses denote the number of fibres from four control and four Cmpt animals.
Tpassive: passive isometric tension; Tactive: active isometric tension; ktr: rate constant of force redevelopment; pCa50: midpoint of the force-calcium relationship; nH: Hill coefficient