Table 4.
Parameters of the depolarization-evoked calcium transients and of the corresponding calcium release flux
Control (n = 14) | Cmpt (n = 13)# | |
---|---|---|
ΔF/F0 | 2.42 ± 0.03 | 2.07 ± 0.10* |
Δ[Ca2+]T (mm) | 3.06 ± 0.39 | 2.08 ± 0.23* |
Rrel peak (μm ms−1) | 23.7 ± 3.0 | 15.8 ± 2.1* |
Rrel steady level (μm ms−1) | 5.7 ± 0.7 | 3.7 ± 0.5* |
Rrel peak/steady level | 4.3 ± 0.4 | 4.6 ± 0.6 |
Time to peak of Rrel (ms) | 8.9 ± 0.3 | 8.9 ± 0.2 |
Tau of inactivation (ms) | 6.7 ± 0.9 | 8.8 ± 1.3 |
Significant difference at P < 0.05 as compared to control.
Numbers in parentheses denote the number of fibres from three control and three Cmpt animals.
ΔF/F0: amplitude of calcium transient; [Ca2+]T: amount of calcium released from the SR; Rrel: Ca2+ release flux