Table 2. Biomarkers of Oxidative Stress and Damage by Study Arm.^a .

	Pancreatic Cancer Cases (n = 31)	Healthy Unrelated Control (n = 20)	Healthy Related Control (n = 20)	Cancer v. Unrelated Control	Cancer v. Related Control
	Adjusted Mean ± SE	Adjusted Mean ± SE	Adjusted Mean ± SE	p-value	p-value
TACb (mM)	4.50±0.08	4.55±0.10	4.43±0.11	0.66	0.65
Direct DNA Damagec	1.00±0.05	0.70±0.06	0.82±0.07	<0.001	0.046
Oxidative DNA Damage	1.79±0.14	1.56±0.17	1.43±0.19	0.26	0.15
MDAd (µM)	1.24±0.05	1.22±0.06	1.15±0.07	0.81	0.33

^aAdjusted for age and sex;

^bTAC = Total antioxidant capacity;

^cDNA damage (direct and oxidative is expressed as Comet (Olive) tail moment: [(tail mean – head mean)*tail%DNA/100];

^dMDA = malondialdehyde.