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. 2014 Mar 20;9(3):e89974. doi: 10.1371/journal.pone.0089974

Table 3. Incremental cost-effectiveness ratios of including pre-adolescent boys in the childhood vaccination program compared to vaccination of pre-adolescent girls only.

Vaccination strategya
HPV-related outcome(s) included Girls onlyb Girls + boysc
Cervix only $20,600 $145,500
Female cancersd $12,800 $119,300
Female + male cancerse $8,900 $81,700
All HPV-related conditionsf $5,000 $60,100
a

Assumes a cost per dose of $75, exclusive of the administration cost (≈$14 per dose).

b

Compared to no vaccination.

c

Compared to girls-only vaccination.

d

Includes female cervical, vulvar, vaginal, anal and oropharyngeal cancers,

e

Includes male anal, oropharyngeal and penile cancers,

f

Includes cervical, vulvar, vaginal, anal, oropharyngeal and penile cancers related to HPV-16, -18, and genital warts and recurrent respiratory papillomatosis related to HPV-6, -11.