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. 2014 Mar 20;9(3):e91969. doi: 10.1371/journal.pone.0091969

Table 1. Clinical characteristics and pattern of adipocytokine secretion in the patients with type 2 diabetes.

Women Men Total
No 49 No 42 No 91
Mean ± SD Mean ± SD Mean ± SD
Age (years) 62.37±6.67 62.12±6.10 62.25±6.38
Duration of disease (years) 9.53±6.50 9.95±5.40 9.73±5.99
BMI (Kg/m2) 30.35±4.94* 28.36±4.09 29.43±4.65
Waist Circumference (cm) 103.02±12.43 101.93±10.10 102.52±11.36
Hip Circumference (cm) 110.30±11.66* 103.66±7.40 107.24±10.42
Waist/Hip ratio 0.93±0.10* 0.98±0.04 0.95±0.08
Body Adiposity Index 37.09±6.27** 30.31±4.17 33.96±6.35
Visceral Adiposity Index 2.64±1.56* 1.87±0.94 2.29±1.36
HbA1c (%) 6.94±0.68 6.88±0.57 6.92±0.63
HbA1c (mmol/mol) 52±7.40 52±6.20 52±6.90
HOMA-IR 2.98±3.02 3.26±3.44 3.11±3.21
Fasting Insulin (pmol/l) 61.75±63.33 68.94±72.31 65.07±67.33
Fasting C-peptide (nmol/l) 0.14±0.16 0.16±0.15 0.15±0.15
Urinary Albumin-to-Creatinine Ratio (UACR) (mg/g) 16.13±47.53 17.05±26.31 16.55±38.99
Fasting lipids
Total Cholesterol (mmol/l) 4.67±0.78 4.53±0.97 4.60±0.87
HDL Cholesterol (mmol/l) 1.31±0.31 1.20±0.32 1.25±0.32
LDL Cholesterol (mmol/l) 2.75±0.82 2.79±0.91 2.77±0.86
Triglycerides (mmol/l) 1.45±0.61 1.36±0.51 1.41±0.57
NEFA (mmol/l) 0.54±0.27* 0.39±0.24 0.47±0.26
Fasting adipocytokines
Leptin (ng/dl)§ 13.74±12.02** 3.59±4.79 9.06±10.65
Soluble leptin receptor (sOb-R) (ng/ml) 19.89±6.18* 23.10±6.40 21.37±6.46
Leptin/sOb-R ratio§ 0.89±1.09** 0.20±0.34 0.57±0.90
Adiponectin (μg/ml) § 10.95±12.10 13.24±14.37 12.01±13.17
Visfatin (ng/ml) 0.64±0.56 0.61±0.50 0.62±0.53
Resistin (ng/ml) § 3.78±4.36 4.42±5.28 4.07±4.79
Ghrelin (pmol/l) 31.49±9.96 30.83±7.66 31.19±8.93
Adipsin (μg/ml) 0.63±0.35 0.70±0.30 0.67±0.33
PAI-1 (ng/ml) 83.51±78.96 83.78±86.79 83.63±82.20
TNF-α (pg/ml) § 1.43±1.62 1.49±1.64 1.46±1.62
IL-6 (pg/ml) 2.24±2.42 2.21±2.18 2.22±2.30
IL-18 (pg/ml) § 41.75±27.32 39.13±24.47 40.54±25.93
VEGF (pg/ml) 106.26±90.91 117.81±104.69 111.59±97.13
HGF (pg/ml) 351.82±185.87 385.22±209.67 367.23±196.80
hs-CRP (mg/l) § 0.50±0.67 0.97±4.44 0.72±3.04

Women vs. Men:

* p<0.05,

**p<0.001; Student’s t Test after testing for equality of variance (Levene test) and after natural log transformation of several variables (§).