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A, A rat performing the ladder rung walking task; B, Walking error rate; C, Walking time and score. Prenatal stress prolonged the time to cross the ladder at baseline and post-lesion periods. Cumulative stress exaggerated the effects of ischemia in limb placement and inter-limb coordination. TS reduced limb placement errors and improved time measurements and scores. *p<0.05, **p<0.01, ***p<0.001.
