Table 2. Peripheral blood mononuclear cell phenotype characteristics throughout pregnancy and in non-pregnant women.
Non-pregnant | 1st trimester | 2nd trimester | 3rd trimester | P-value | |
CD3+ T cells | 66,64±2,23 | 65,10±3,27 | 69,43±3,33 | 67,74±1,34 | NS |
CD4+ T cells | 44,04±2,32 | 39,92±2,28 | 45,68±3,47 | 39,03±2,60 | NS |
CD8+ T cells | 32,02±1,51 | 35,25±1,53 | 28,98±2,67 | 34,31±2,41 | NS |
CD8+ TIM-3+ T cells | 5,59±0,83 | 6,0±0,89 | 4,36±0,88 | 5,97±0,50 | NS |
CD3- CD56+ cells | 13,65±1,38 | 12,31±1,85 | 10,69±1,74 | 11,47±1,53 | NS |
CD3- CD56dim cells | 12,72±1,31 | 10,56±1,75 | 9,29±1,69 | 9,74±1,39 | NS |
CD3- CD56bright cells | 1,03±0,24 | 1,80±0,29 | 1,44±0,30 | 1,76±0,24 | NS |
CD3- CD56+ TIM-3+ cells | 9,61±1,41 | 9,16±1,53 | 7,34±1,30 | 9,05±1,30 | NS |
CD3- CD56dim TIM-3+ cells | 9,02±1,38 | 8,10±1,42 | 6,49±1,25 | 8,07±1,23 | NS |
CD3- CD56bright TIM-3+ | 0,61±0,18 | 1,11±0,22 | 0,93±0,24 | 1,11±0,17 | NS |
CD3+ CD56+ cells | 4,08±0,75 | 6,37±1,21 | 4,70±0,98 | 5,46±1,26 | NS |
Gal-9+ Th cells | 0,97±0,13 | 0,66±0,09 | 1,17±0,3 | 2,39±0,49 | 3rd vs. NP p<0,01 3rd vs. 1st p<0,01 3rd vs. 2nd p<0,03 |
Statistical comparisons were made by using the ANOVA tests. The results were expressed as the mean value±standard error of the mean (SEM). Differences were considered significant when the value of p was equal to or less than 0.05. NS = not statistically significant.