(A) Levels of total cell-specific MP in plasma at time of CM onset: platelet-MP (PMP, white), endothelial-MP (EMP, light grey), erythrocytic-MP (EryMP, dark grey), monocytic-MP (MMP, black), leucocytic-MP (LMP, striped). (B–F) Cell-specific MP levels per µL of plasma at time of CM onset: non-infected (white bar), PbK (light grey bar), PbK1/2 (dark grey bar), PbA (black bar). B. PMP. C. EMP. D. RMP. E. MMP. F. LMP. Data shown from n = 25 healthy, n = 20 PbK infected and n = 10 PbK1/2 infected mice showing signs of CM on day 6 and 7 p.i. and from n = 23 PbA infected mice collected on day 6, 7 and 8 p.i., and represented as mean ± SEM. *p<0.05, **p<0.001, ***p<0.0001.