Table II.

Risk stratification (the TCCSG L04-16 Study).

A, B-lineage ALL
	Years
Initial risk	1–6	7–9	≥10
Initial leukocyte count, ×109/l
<20	SR	IR	IR
20–49	IR	IR	IR
50–99	IR	IR	HR
≥100	HR	HR	HR
B, B-lineage ALL
	Days
Day 8 risk	1 SR	1 IR	1 HR
Day 8 PB blasts/μl
0–999	SRa	IRa	HR
≥1,000	HR	HR	Allo-SCT
C, T-lineage ALL
Day 8 risk			All patients
Day 8 PB blasts/μl
0–999			HR
≥1,000			Allo-SCT

^aPatients were assigned to high-risk group if >5 cells/μl were counted in the cerebrospinal fluid and lymphoblasts were identified or if intracranial infiltrates were detected on brain imaging studies.

Diagnostic lumbar puncture was performed on day eight in remission induction therapy. PB, peripheral blood; SR, standard-risk; IR, intermediate-risk; HR, high-risk; Allo-SCT, allogeneic stem cell transplantation.