Skip to main content
. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Invest Dermatol. 2013 Sep 20;134(4):1033–1043. doi: 10.1038/jid.2013.401

Figure 5. Dsg3 cytoplasmic sequences mediate co-localization with DP and differential sensitivity to detergent pre-extraction.

Figure 5

(a–h) Images of IL-2R and IL-2RDsg3 chimeras expressed in keratinocytes, with and without PKP-1.myc co-expression. Cells were labeled live with a mAb IL-2R (red and a′–h′) for 30 minutes and then immediately subjected to a 45 second detergent pre-extraction with 0.2% Triton-X100. Following fixation, the cells were immunostained for total DP (green and a″–h″) and myc (blue and e′″–h′″). Scale bars 20Hm.