Table 1.
Demographic data by diagnostic and genotype groups
| CON | MCI | AD | Total | ||
|---|---|---|---|---|---|
| 0 APOE ε 4 allele | N0 | 151 (68 F) | 162 (56 F) | 60 (31 F) | 373 (155 F) |
| N12 | 130 (56 F) | 138 (49 F) | 45 (22 F) | 313 (127 F) | |
| N24 | 112 (52 F) | 98 (36 F) | 31 (16 F) | 241 (104 F) | |
| Age | 76.10 (± 5.16) | 76.27 (± 7.66) | 77.15 (± 8.53) | 76.34 (± 6.92) | |
| MMSE | 29.15 (± 0.94) | 27.24 (± 1.77) | 23.17 (± 2.07) | 27.36 (± 2.55) | |
| 1 APOE ε 4 allele | N0 | 50 (24 F) | 153 (54 F) | 79 (33 F) | 282 (111 F) |
| N12 | 46 (22 F) | 129 (45 F) | 62 (28 F) | 237 (95 F) | |
| N24 | 40 (20 F) | 94 (29 F) | 49 (21 F) | 183 (70 F) | |
| Age | 76.54 (± 4.52) | 74.85 (± 6.79) | 75.97 (± 6.52) | 75.46 (± 6.38) | |
| MMSE | 29.18 (± 1.02) | 27.01 (± 1.75) | 23.48 (± 2.02) | 26.40 (± 2.64) | |
| 2 APOE ε 4 alleles | N0 | 4 (2 F) | 43 (18 F) | 34 (14 F) | 81 (34 F) |
| N12 | 4 (2 F) | 39 (16 F) | 29 (11 F) | 72 (29 F) | |
| N24 | 4 (2 F) | 30 (11 F) | 21 (8 F) | 55 (21 F) | |
| Age | 73.75 (± 3.86) | 71.81 (± 5.98) | 71.91 (± 7.28) | 71.95 (± 6.43) | |
| MMSE | 29.00 (± 0.82) | 26.84 (± 1.98) | 23.44 (± 1.86) | 25.52 (± 2.62) | |
| Total | N0 | 205 (94 F) | 358 (128 F) | 173 (78 F) | 736 (300 F) |
| N12 | 180 (80 F) | 306 (110 F) | 136 (61 F) | 622 (251 F) | |
| N24 | 156 (74 F) | 222 (76 F) | 101 (45 F) | 479 (195 F) | |
| Age | 76.16 (± 4.99) | 75.13 (± 7.23) | 75.58 (± 7.61) | 75.52 (± 6.79) | |
| MMSE | 29.16 (± 0.95) | 27.09 (± 1.79) | 23.36 (± 2.00) | 26.79 (± 2.67) | |
N0, N12, and N24 indicate sample sizes at baseline, 12-month follow-up, and 24-month follow-up, respectively. Sample sizes are followed by the number of women in parentheses. Age and MMSE indicate baseline age and scores on the mini mental status examination. Means are followed by standard deviations in parentheses.