Table 4.

Feeding and sedation parameters in preterm lambs managed by invasive or non-invasive respiratory support (mean ± SD)

Parameter	Preterm 3d (n=5 each)			Preterm 21d (n=4 each)
	Day of life	Intubation and IMV	HFNV	Week of life	Intubation and IMV	HFNV
Plasma glucose (gm/dL)	1	101 ± 75	118 ± 46	1	84 ± 20	95 ± 10
	2	96 ± 32	109 ± 30	2	81 ± 20	105 ± 7
	3	83 ± 25	93 ± 13	3	84 ± 7	99 ± 6
Enteral feeding (mL/Kg/d)a	1	13 ± 9	9 ± 7	1	106 ± 10	107 ± 10
	2	35 ± 22	24 ± 15	2	81 ± 55	149 ± 59
	3	51 ± 35	52 ± 31	3	53 ± 23	188 ± 70*
Pentobarbital (mg/Kg/d)	1	7 ± 4	4 ± 4	1	24 ± 20	1 ± 1*
	2	2 ± 2	1 ± 1	2	29 ± 31	1 ± 1
	3	4 ± 2	2 ± 1	3	73 ± 64	1 ± 1*
Buprenorphine (mcg/Kg/d)	1	0.04 ± 0.01	0.04 ± 0.01	1	0.06 ± 0.02	0.03 ± 0.03*
	2	0.04 ± 0.03	0.05 ± 0.01	2	0.06 ± 0.01	0.03 ± 0.03*
	3	0.05 ± 0.01	0.05 ± 0.01	3	0.05 ± 0.01	0.01 ± 0.01*

^aEwe’s colostrum (days of life 1–3) followed by ewe’s maturing milk (day of life 4 and thereafter).

^*Statistically different from IMV group by unpaired t-test, p<0.05.