Table 1.
SNPs previously associated with FTLD-tau or FTLD-TDP included in the neuroimaging analysis and their risk allele frequencies.
| Disorder | Ch | SNP | Gene | Risk Allele | Risk Allele Frequency |
|---|---|---|---|---|---|
|
| |||||
| FTLD-TAU | 17 | rs1052553 | MAPT | G | 18.51% (30) |
| FTLD-TAU (PSP) | 12 | rs11568563 | SLCO1A2 | G | 9.52% (16) |
| FTLD-TAU (PSP) | 6 | rs12203592 | IRF4 | T | 22.58% (35) |
| FTLD-TAU (PSP) | 1 | rs1411478 | STX6 | A | 24.11% (34) |
| FTLD-TAU (PSP) | 3 | rs1768208 | MOBP | T | 45.83% (66) |
| FTLD-TAU (PSP) | 10 | rs2142991 | BMS1 | C | 20.25% (32) |
| FTLD-TAU (PSP) | 17 | rs242557 | MAPT | A | 31.34% (36) |
| FTLD-TAU (PSP) | 6 | rs2493013 | EXOC2 | A | 8.97% (14) |
| FTLD-TAU (PSP) | 2 | rs6547705 | CD8B | G | 23.57% (37) |
| FTLD-TAU (PSP) | 1 | rs6687758 | Intergenic | G | 25.16% (39) |
| FTLD-TAU (PSP) | 4 | rs6852535 | IL2/IL21 | A | 16.00% (24) |
| FTLD-TAU (PSP) | 2 | rs7571971 | CD8B/EIF2AK3 | T | 26.45% (41) |
| FTLD-TAU (PSP) | 17 | rs8070723 | MAPT | A | 79.75% (130) |
| TAU | 2 | rs4499362 | EPC2 | T | 22.50% (36) |
| FTLD-TDP | 7 | rs1020004 | TMEM106B | C | 36.91% (55) |
| FTLD-TDP | 7 | rs1990622 | TMEM106B | A | 27.40% (40) |
| FTLD-TDP/ALS | 9 | rs2814707 | C9orf72 | T | 5.16% (8) |
| FTLD-TDP | 7 | rs3173615 | TMEM106B | C | 72.60% (106) |
| FTLD-TDP/ALS | 9 | rs3849942 | C9orf72 | T | 5.19% (8) |
| FTLD-TDP | 17 | rs5848 | GRN | T | 18.57% (26) |
| FTLD-TDP | 1 | rs646776 | SORT1/CELSR2/PSRC1 | C | 27.89% (41) |