Table 2.

OCB Peptides and Associated IgG-VH Clusters

Patient ID	OCB Peptides	Associated IgG-VH Clusters	CSF-Restricted IgG-VH Clusters
MS-1	7	6	5
MS-2	20	14	13
MS-3	38	20	20
MS-4	3	2	2
MS-5	12	10	4

Shown are numbers of OCB peptides that could be uniquely assigned to a specific patient in our IgG-VH reference database and associated IgG-VH clusters. CSF-restricted IgG-VH clusters are those in which OCB peptides mapped to IgG-VH sequence clusters that were exclusively found in the CSF.

CSF = cerebrospinal fluid; IgG-VH = IgG heavy chain variable region; OCB = oligoclonal band.