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Chromosome aberrations of Pu27-treated normal peripheral lymphocytes
| Sample | Total metaphases studied | Abnormal metaphases | Chromatid breaks | Chromosome breaks | Cells with radials and extensive break | No. breaks/metaphase (excluding radials) |
|---|---|---|---|---|---|---|
| UNT | 119 | 4 (3.4%) | 5 (4.2%) | 2 (1.7%) | 0 | 0.06 |
| Pu27 day 1 | 129 | 12 (9.3%) | 11 (8.5%) | 2 (1.6%) | 0 | 0.1 |
| Pu27 day 3 | 134 | 19 (14.2%) | 12 (9%) | 14 (10.4%) | 0 | 0.19 |
| Pu27 day 5 | 141 | 26 (18.4%) | 27 (19.1%) | 18 (12.8%) | 5 (3.5%) | 0.32 |
