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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: ESPEN J. 2014 Apr 1;9(2):e76–e83. doi: 10.1016/j.clnme.2014.01.003

Table 4.

Results from final model for mortality for 30 and 90 days after ICU admission.

Covariate 30-day mortality OR (95% CI) P-value 90-day mortality OR (95% CI) P-value
B12, pmol/l (Ref=Mid- range) 0.6626 0.5719
 Deficient B12 1.28 (0.31, 5.32) 0.7363 1.27 (0.37, 4.41) 0.7060
 High B12 1.18 (0.81, 1.72) 0.3886 1.20 (0.84, 1.70) 0.3148
Age, years (Ref=45–65) <0.0001 <0.0001
 <45 0.46 (0.24, 0.90) 0.0224 0.48 (0.26, 0.88) 0.0181
 65–80 1.97 (1.22, 3.15) 0.0051 2.25 (1.47, 3.44) 0.0002
 ≥80 6.44 (3.82, 10.85) <0.0001 7.22 (4.48, 11.63) <0.0001
Gender (Ref=Female) 0.94 (0.68, 1.30) 0.7200 1.18 (0.88, 1.58) 0.2725
Race (Ref=White) 0.4647 0.4164
 Black 0.71 (0.41, 1.25) 0.2363 0.73 (0.44, 1.20) 0.2141
 Other 1.02 (0.67, 1.54) 0.9307 0.89 (0.60, 1.31) 0.5490
Insurance type (Ref=Insured) 0.0128 0.2368
 Medicaid/Self-pay 1.67 (0.94, 2.96) 0.0819 1.25 (0.74, 2.12) 0.4017
 Medicare 1.42 (0.94, 2.16) 0.0982 1.17 (0.81, 1.70) 0.4081
 Other 4.66 (1.72, 12.61) 0.0025 2.65 (1.01, 6.95) 0.0469
Dialysis - - 1.82 (1.19, 2.80) 0.0062
SAPS 1.09 (1.06, 1.13) <0.0001 1.08 (1.05, 1.11) <0.0001
First service unit (Ref=CCU) <0.0001 <0.0001
 CSRU 0.32 (0.15, 0.68) 0.0031 0.37 (0.19, 0.72) 0.0032
 MICU 1.14 (0.67, 1.94) 0.6254 1.05 (0.66, 1.67) 0.8416
 SICU 0.19 (0.08, 0.47) 0.0004 0.38 (0.18, 0.77) 0.0072
B12 supplement 0.49 (0.21, 1.13) 0.0941 - -
Sepsis 1.39 (0.96, 2.03) 0.0839 1.46 (1.03, 2.07) 0.0330
TPN - - 2.11 (0.92, 4.85) 0.0780
Respiratory disease - - 1.72 (1.17, 2.52) 0.0060
Stroke 3.77 (2.25, 6.32) <0.0001 3.21 (1.98, 5.21) <0.0001
CAD 0.77 (0.51, 1.15) 0.2015 0.58 (0.40, 0.84) 0.0037
Hypertension - - 0.79 (0.58, 1.07) 0.1310
Other CVD - - 1.42 (1.02, 1.98) 0.0354
Immunocompromised 2.30 (1.62, 3.26) <0.0001 2.43 (1.76, 3.36) <0.0001
Alcoholism 1.66 (1.07, 2.59) 0.0244 - -
MCV, fL (Ref≤86) 0.0529 0.0455
 Q2 (86, 91] 0.91 (0.57, 1.45) 0.6832 0.82 (0.54, 1.24) 0.3439
 Q3 (91, 96] 1.05 (0.64, 1.70) 0.8583 0.93 (0.60, 1.44) 0.7403
 Q4 (96, 135] 1.57 (1.00, 2.47) 0.0487 1.39 (0.93, 2.09) 0.1063
Inotropic support 1.53 (1.03, 2.27) 0.0331 - -
Neuropsychiatric disorder 0.70 (0.49, 1.01) 0.0561 - -
ALT, IU/l (Ref≤15) 0.3293 0.6625
 Q2 (15, 24] 1.21 (0.74, 1.99) 0.4535 1.18 (0.76, 1.83) 0.4598
 Q3 (24, 43] 1.62 (0.96, 2.73) 0.0683 1.35 (0.84, 2.16) 0.2179
 Q4 (43, 4170] 1.40 (0.76, 2.58) 0.2828 1.19 (0.68, 2.08) 0.5407
AST, IU/l (Ref≤20) 0.8722 0.7431
 Q2 (20, 29] 1.20 (0.70, 2.05) 0.5086 1.13 (0.71, 1.80) 0.6009
 Q3 (29, 58.2] 1.03 (0.59, 1.79) 0.9273 0.90 (0.55, 1.48) 0.6861
 Q4 (58.2, 4253] 1.14 (0.58, 2.24) 0.6997 1.04 (0.57, 1.91) 0.8996
TB, mg/dl (Ref≤0.4) 0.0335 0.0165
 Q2 (0.4, 0.6] 1.49 (0.93, 2.38) 0.0966 1.32 (0.86, 2.02) 0.2075
 Q3 (0.6, 1.1] 0.99 (0.61, 1.60) 0.9629 1.33 (0.87, 2.03) 0.1888
 Q4 (1.1, 54.2] 1.81 (1.12, 2.94) 0.0160 2.06 (1.32, 3.21) 0.0014
ALP, IU/L (Ref≤66) 0.0156 0.0430
 Q2 (66, 85] 1.29 (0.77, 2.16) 0.3367 1.48 (0.94, 2.34) 0.0896
 Q3 (85, 121] 1.85 (1.13, 3.03) 0.0140 1.66 (1.07, 2.58) 0.0248
 Q4 (121, 4585] 2.02 (1.23, 3.29) 0.0052 1.85 (1.19, 2.89) 0.0065
ALB, g/dl (Ref≤2.8) <0.0001 <0.0001
 Q2 (2.8, 3.3] 0.92 (0.63, 1.32) 0.6427 0.81 (0.57, 1.13) 0.2156
 Q3 (3.3, 3.8] 0.45 (0.28, 0.71) 0.0007 0.38 (0.25, 0.58) <0.0001
 Q4 (3.8, 5.6] 0.28 (0.14, 0.53) 0.0001 0.24 (0.14, 0.43) <0.0001
PT, second (Ref≤13.3) 0.4065 0.8901
 Q2 (13.3, 14.6] 1.09 (0.68, 1.74) 0.7338 1.02 (0.67, 1.56) 0.9164
 Q3 (14.6, 16.7] 0.95 (0.58, 1.58) 0.8555 1.00 (0.64, 1.56) 0.9989
 Q4 (16.7, 150] 1.34 (0.84, 2.13) 0.2221 1.15 (0.75, 1.76) 0.5305
Liver disease 1.61 (0.99, 2.61) 0.0531 1.71 (1.09, 2.67) 0.0197
Liver cancer 2.31 (0.97, 5.46) 0.0576 3.54 (1.52, 8.26) 0.0035