Table 3. Comparison of various modalities with gene expression in terms of proportion of dataset/tasks where two modalities achieve ‘statistically optimal’ AUC.
| Number of datasets/tasks | Comparison of proportions | ||||
|---|---|---|---|---|---|
| Modality | where this modality was measured | where this modality had ‘statistically optimal’ performance | where gene expression had ‘statistically optimal’ performance | p-value | p-value adjusted for multiple comp. |
| Clinical | 47 | 15 | <43 | <10−5 | <10−5 |
| Protein expression | 27 | 22 | <25 | 0.2242 | 0.3587 |
| Somatic Mutations | 16 | 9 | <14 | 0.0493 | 0.0986 |
| DNA Methylation | 27 | 23 | <25 | 0.3865 | 0.5153 |
| miRNA Expression | 14 | 14 | = 14 | 1 | 1 |
| Copy Number | 3 | 0 | <3 | 0.0143 | 0.0381 |
| Tumor Imaging | 1 | 1 | = 1 | 1 | 1 |
| GWAS | 16 | 1 | <14 | <10−5 | 1.6483·10−5 |