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Experimental Approach Used in Figure 6
| Panel | Pre-DC | Host | Result |
|---|---|---|---|
| B | HO-1+/+ | HO-1+/+ | Control: generation of CD8+ DC from transferred pre-DC |
| A | HO-1+/+ | HO-1−/− | HO-1+/+ CD8+ DC fail to develop in the HO-1−/− spleen |
| E | HO-1−/− | HO-1+/+ | HO-1−/− CD8+ DC develop normally the in HO-1+/+ spleen |
| D | HO-1−/− | HO-1−/− | HO-1−/− CD8+ fail to develop from the in HO-1−/− spleen |
