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Nrf2 level influences the expression of genes involved in neovascularization. PACs were cultured for 24 h under normoxia or hypoxia (0.5% O2). The mRNA level of several genes differentially regulated in PAC Nrf2+/+ and Nrf2−/− is shown (A–K). Transcriptome analysis, PCR array. Each bar represents the mean±SEM (nNrf2+/+=2–3; nNrf2−/−=2–3). *p<0.05, normoxia versus hypoxia; #p<0.05, Nrf2+/+ versus Nrf2−/−.
