Figure 2.

Multiple sequence alignment of the murine, human and equine MD-2 sequences (chain c in 3FXI) [18, 30]. The human sequence was extracted from the crystal structure [18] which served as the 3D template for the mouse and horse models. The canine sequence entry, however, is available as a theoretical prediction. A comment line above the MSA blocks refers to residues discussed in the text (underlined, bold face).