Table 3.
Protein sequence identities of TLR4 and MD-2 for human, murine, equine and canine species by Clustal W [30]. The TLR4 residue lengths are 839, 835, 843 or 833, respectively and 160 for each MD-2 sequence. However, only a theoretical canine protein MD-2 sequence was found at Universal Protein Resource at www.uniprot.org, last visit March 2013).
| Subunit | Subunit | id score |
|---|---|---|
| cTLR4 | eTLR4 | 79% |
| hTLR4 | eTLR4 | 77% |
| hTLR4 | cTLR4 | 73% |
| hTLR4 | mTLR4 | 66% |
| eTLR4 | mTLR4 | 66% |
| cTLR4 | mTLR4 | 64% |
| cMD-2 (theoretical) | eMD-2 | 71% |
| hMD-2 | cMD-2 | 71% |
| hMD-2 | eMD-2 | 65% |
| hMD-2 | mMD-2 | 63% |
| eMD-2 | mMD-2 | 60% |
| cMD-2 (theoretical) | mMD-2 | 65% |