Table 3.

Listing of available crystal structures concerning the biological unit of TLR4/MD-2.

PDB Code Year Ref	Species ( Components in complex) TITLE	Resolution (Å)
2E59	Human (MD-2 / L4a)1
2006	CRYSTAL STRUCTURE OF HUMAN MD-2 IN COMPLEX WITH LIPID IVA	2.21
[11]
2E56	Human (MD-2)1
2006	CRYSTAL STRUCTURE OF HUMAN MD-2	2
[11]
2Z62	Human (TLR4 fragment)1
2007	CRYSTAL STRUCTURE OF THE TV3 HYBRID OF HUMAN TLR4 AND HAGFISH VLRB.61	1.7
[12]
2Z63	Human (TLR4 fragment)1
2007	CRYSTAL STRUCTURE OF THE TV8 HYBRID OF HUMAN TLR4 AND HAGFISH VLRB.61	2
[12]
2Z64	Mouse (TLR4 fragment / MD-2)1
2007	CRYSTAL STRUCTURE OF MOUSE TLR4 AND MOUSE MD-2 COMPLEX	2.84
[9]
2Z65	Human (TLR4 / MD-2 / Eri)2
2007	CRYSTAL STRUCTURE OF THE HUMAN TLR4 TV3 HYBRID-MD-2-ERITORAN COMPLEX	2.7
[12]
2Z66	Human (TLR4 fragment)4
2007	CRYSTAL STRUCTURE OF THE VT3 HYBRID OF HUMAN TLR4 AND HAGFISH VLRB.61	1.9
[12]
3FXI	Human (TLR4 / MD-2 / Ra-LPS)2
2009	CRYSTAL STRUCTURE OF THE HUMAN TLR4-HUMAN MD-2-E.COLI LPS RA COMPLEX	3.1
[8]
3MU3	Chicken (MD-1 / L4a)2
2010	CRYSTAL STRUCTURE OF CHICKEN MD-1 COMPLEXED WITH LIPID IVA	2.4
[13]
3MTX	Chicken (MD-1 / - * -)2
2010	CRYSTAL STRUCTURE OF CHICKEN MD-1	2
[13]	(* but MD-1 is liganded)
3VQ1	Mouse (TLR4/MD-2/L4a)2
2012	CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID IVA COMPLEX	2.7
[15]
3VQ2	Mouse (TLR4/MD-2/LPS)2
2012	CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX	2.48
[15]