Table 2.

Efficacy parameters

	Intent-to-treat		LEN refractory		LEN and BORT refractory
	POM+LoDEX (n = 113)	POM alone (n = 108)	POM+LoDEX (n = 88)	POM alone (n = 86)	POM+LoDEX (n = 70)	POM alone (n = 66)
Median PFS, months	4.2	2.7	3.8	2.2	3.8	2.0
Median OS, months	16.5	13.6	16.0	12.0	13.4	12.5
ORR (≥PR), %	33	18	30	21	31	21
≥MR, %	45	31	42	31	46	33
CR	3	2	0	1	0	1
PR	30	16	30	20	31	20
MR	12	13	13	11	14	12
SD, %	37	48	41	47	39	42
Median time-to-response (≥PR), months	1.9	4.3	1.9	4.6	1.6	4.6
Median duration of response (≥PR), months	8.3	10.7	7.7	8.8	6.5	11.4
Median duration of ≥MR, months	7.7	7.4	6.2	6.7	6.2	6.7

CR, complete response; MR, minimal response.