Table 1.
Characteristic | Bone marrow | PBSC | P | ||
---|---|---|---|---|---|
N | % | N | % | ||
No. of donors | 2726 | 6768 | |||
No. of donor centers | 81 | 76 | |||
No. of collection centers | 83 | NA | |||
No. of apheresis centers | NA | 98 | |||
Donor sex | .168 | ||||
Male | 1638 | 60 | 4170 | 62 | |
Female | 1088 | 40 | 2598 | 38 | |
Donor race/ethnicity | <.001 | ||||
White | 1935 | 71 | 5083 | 75 | |
Hispanic | 294 | 11 | 582 | 9 | |
Black | 165 | 6 | 320 | 5 | |
Asian/Pacific Islander | 144 | 5 | 294 | 4 | |
American Indian/Alaska Native | 42 | 2 | 77 | 1 | |
Other/multiple race | 130 | 5 | 351 | 5 | |
Decline/unknown | 16 | 1 | 61 | 1 | |
Donor age at donation, y | .100 | ||||
18-30 | 973 | 36 | 2380 | 35 | |
31-40 | 878 | 32 | 2202 | 33 | |
41-50 | 684 | 25 | 1616 | 24 | |
51-61 | 191 | 7 | 570 | 8 | |
Median, range | 35 | 18-61 | 35 | 18-61 | .377 |
Donor BMI, kg/m2 | .646 | ||||
Underweight (<18.5) | 14 | 1 | 41 | 1 | |
Normal (18.5-24.9) | 825 | 30 | 1970 | 29 | |
Overweight (25-29.9) | 1044 | 38 | 2659 | 39 | |
Obese (≥30) | 843 | 31 | 2097 | 31 | |
Unknown | 0 | 1 | NA | ||
Median, range | 27.4 | 16.1-50.9 | 27.4 | 16.2-56.2 | .899 |
Donor CMV | <.001 | ||||
Nonreactive | 1554 | 57 | 4124 | 61 | |
Reactive | 1172 | 43 | 2642 | 39 | |
Unknown/indeterminate | 0 | 2 | NA | ||
Donor WBC counts at baseline | |||||
Median, range | 6.4 | 2.3-14.2 | 6.3 | 2.3-16.0 | .544 |
Donor neutrophil counts at baseline | |||||
Median, range | 4.0 | 1.0-12.5 | 4.0 | 1.0-12.9 | .276 |
Donor MNC counts at baseline | |||||
Median, range | 2.3 | 0.9-7.2 | 2.3 | 0.3-7.3 | .633 |
Donor platelet counts at baseline | |||||
Median, range | 254 | 104-534 | 254 | 100-548 | .869 |
Donor hemoglobin level at baseline | |||||
Male, median, range | 15.3 | 11.1-18.3 | 15.3 | 10.9-19.0 | .800 |
Female, median, range | 13.5 | 8.6-19.0 | 13.4 | 9.4-16.5 | .886 |
Year of donation | <.001 | ||||
2004 | 491 | 18 | 814 | 12 | |
2005 | 449 | 16 | 1102 | 16 | |
2006 | 479 | 18 | 1188 | 18 | |
2007 | 471 | 17 | 1297 | 19 | |
2008 | 537 | 20 | 1497 | 22 | |
2009 | 299 | 11 | 870 | 13 |
NMDP indicates National Marrow Donor Program; NA, not applicable; and WBC, white blood cell.