Table 1.
Edge strands and central strands of the human transthyretin structure. Extreme values of the number of SOF (Vm) highlighted in bold predict the edge strands noted in bold. The position of the strand in the sheet is central (C) or on the edge (E). Amino acids in the single-letter code are numbered according to the structure (PDB reference 1eta) [48].
| Beta-strand | Position | Vm |
|---|---|---|
| P11-D18 | C2 | 1.9 |
| G53-H56 | E2 | 4.3 |
| R103-S112 | C1 | 1.1 |
| S115-T123 | E1 | 1 |
| V28-A36 | C1 | 3 |
| A45-T49 | E1 | 3.6 |
| E66-D74 | C2 | 2.8 |
| H90-A97 | E2 | 2.3 |