Skip to main content
. Author manuscript; available in PMC: 2014 Mar 21.
Published in final edited form as: Mamm Genome. 2009 Feb 10;20(3):162–169. doi: 10.1007/s00335-009-9172-y

Table 1.

Association of Iddm14 genotype and diabetes susceptibility in (LEW.1WR1 × WF.ART2a/a)F2 rats

Iddm14 genotype Number diabetic (%) Number nondiabetic (%) Totals
L/L 10 (50) 10 (50) 20
L/W 19 (43) 25 (57) 44
W/W 0 (0) 11 (100) 11
Totals 29 (39) 46 (61) 75

L = LEW.1WR1-origin allele of Iddm14; W = WF.ART2a/a-origin allele

(LEW.1WR1 × WF)F2 rats were bred, treated with poly I:C to induce diabetes, and genotyped to determine the origin of Iddm14 alleles as described in Methods. All diabetic animals were found to have inherited at least one LEW.1WR1-origin allele of Iddm14 (p <0.01)