Table 1.
Chemokines and chemokine receptors
| Cell type | Receptor | Chemokinea |
|---|---|---|
| Eosinophil Monocyte Activated T cell Dendritic cell | CCR1 | MCP-3 (CCL7), MCP-4 (CCL13), MIP-1α (CCL3), RANTES (CCL5), HCC-1 (CCL14) |
| Basophil Monocyte Activated T cell Dendritic cell NK cell | CCR2 | MCP-1 (CCL2), MCP-2 (CCL8), MCP-3 (CCL7), MCP-4 (CCL13), MCP-5 (CCL12) |
| Eosinophil Basophil Dendritic cell Activated T cell Resting T cell | CCR3 | Eotaxin-1 (CCL11), Eotaxin-2 (CCL24), MCP-3 (CCL7), MCP-4 (CCL13), RANTES (CCL5), PARC (CCL18) |
| Activated T cell Dendritic cell | CCR4 | TARC (CCL17), MDC (CCL22) |
| Monocyte Activated T cell Dendritic cell NK cell | CCR5 | MIP-1α (CCL3), MIP-1β (CCL4), RANTES (CCL5), HCC-1 (CCL14) |
| Dendritic cell | CCR6 | MIP-3α (CCL20) |
| Activated T cell Resting T cell | CCR7 | MIP-3β (CCL19), SLC (CCL21) |
| Monocyte | CCR8 | I-309 (CCL1) |
| Activated T cell Resting T cell Monocyte Dendritic cell | CCR9 | TECK (CCL25) |
| Monocyte activated T cell NK cell | CX3CR1 | Fractalkine (CX3CL1) |
| Neutrophil | CXCR1 | IL-8 (CXCL8), GCP-2 (CXCL6) |
| Neutrophil | CXCR2 | IL-8 (CXCL8), GCP-2 (CXCL6), GRO-α (CXCL1), GRO-β (CXCL2), GRO-γ (CXCL3), ENA-78 (CXCL5), NAP-2 (CXCL7) |
| Activated T cell NK cell | CXCR3 | IP-10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) |
| Monocyte Resting T cell Dendritic cell | CXCR4 | SDF-1 (CXCL12) |
| NK cell Activated T cell Dendritic cell | XCR1 | Lymphotactin (XCL1), SCM-1β (XCL2) |
a
Chemokines are identified with both common names and systematic names in parenthesis. Bold font identifies inflammatory/inducible chemokines. Homoeostatic chemokines are shown in italic font. Bold and italic font denotes chemokines belonging to both classifications.