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. Author manuscript; available in PMC: 2014 Mar 21.
Published in final edited form as: Stem Cells. 2009 Mar;27(3):533–542. doi: 10.1634/stemcells.2008-0596

Figure 7.

Figure 7

hESC survival is mediated by alteration in components of mitogen-activated protein kinase (MAPK) and p53 activity. Examination of MAPK transcription factor activity in the shRNA- or HA-treated cells as demonstrated using Eppendorf's MAPK Transcription Factor chromatin immunoprecipitation kit. Activity of p53 but not other MAPK components was decreased in the HA-treated or shRNA-Rho-kinase hESCs. *, The decrease in p53 activity was statistically significant at p ≤ .0085. Abbreviations: HA, HA-1077; hESC, human embryonic stem cell; shRNA, short hairpin RNA.