Table 3. Results of Cosinor Analysis of Circadian Gene mRNA Expression.

Gene of Interest	Significant Difference
	Phase	Amplitude	Maxima	Minima
CLOCK	Ob_Con vs Ob_Ob (p = 0.009)	No	No	No
BMAL 1	No	Con_Con vs Con_Ob (p = 0.016)	Con_Con vs Con_Ob (p = 0.013)	No
		Con_Con vs Ob_Ob (p = 0.028)
Per 1	No	No	No	No
Per 2	Ob_Con vs Ob_Ob (p = 0.026)	Con_Con vs Ob_Con (p = 0.017)	Con_Con vs Con_Ob (p = 0.013)	Con_Con vs Ob_Ob (p = 0.002)
		Con_Con vs Ob_Ob (p = 0.005)
REV-ERB α	Con_Con vs Con_Ob (p = 0.002)	No	No	No
	Con_Con vs Ob_Ob (p = 0.002)