Table 1. Association of hBD-1 expression in OSCC with patients' clinicopathological characteristics (n = 175).
Total n | Negative n (percentage) | Weak n (percentage) | Strong n (percentage) | P value | |
Gender | |||||
Female | 50 | 15 (30.0%) | 24 (48.0%) | 11(22.0%) | 0.065 |
Male | 125 | 58 (46.4%) | 53 (42.4%) | 14 (11.2%) | |
Age (year) | |||||
<60 | 85 | 38 (44.7%) | 39 (45.9%) | 8 (9.4%) | 0.198 |
≥60 | 90 | 35 (38.9%) | 38 (42.2%) | 17 (18.9%) | |
Smoking status | |||||
Smoker | 97 | 49 (50.5%) | 38 (39.2%) | 10 (10.3%) | 0.029 |
Nonsmoker | 78 | 24 (30.8%) | 39 (50.0%) | 15 (19.2%) | |
Differentiation | |||||
Well | 107 | 29 (27.1%) | 54 (50.5%) | 24 (22.4%) | <0.001 |
Medium/Poor | 68 | 44 (64.7%) | 23 (33.8%) | 1 (1.5%) | |
pT | |||||
T1–T2 | 90 | 35 (38.9%) | 41 (45.5%) | 14 (15.6%) | 0.717 |
T3–T4 | 85 | 38 (44.7%) | 36 (42.4%) | 11 (12.9%) | |
pN | |||||
N0 | 110 | 39 (35.4%) | 51 (46.4%) | 20 (18.2%) | 0.043 |
N1–Nx | 65 | 34 (52.3%) | 26 (40.0%) | 5 (7.7%) | |
Tumor stage | |||||
I | 17 | 5 (29.4%) | 8 (47.1%) | 4 (23.5%) | 0.138 |
II | 45 | 16 (35.5%) | 21 (46.7%) | 8 (17.8%) | |
III | 46 | 21 (45.6%) | 20 (43.5%) | 5 (10.9%) | |
IV | 67 | 31 (46.3%) | 28 (41.8%) | 8 (11.9%) |