Table 3. The deposition of complement components in glomeruli of patients with anti-GBM disease.
Complement | Glomeruli per section (mean±SD) | Glomerular capillary walls, n (%) | Mesangial regions, n (%) | Crescents, n (%) | Bowman's capsules, n (%) | Scores | |||
1 | 2 | 3 | 4 | ||||||
C5b-9 | 5.8±2.3 | 29/29 (100%) | 12/29(41.4%) | 0/29(0%) | 3/29(10.3%) | 2/29 | 6/29 | 15/29 | 6/29 |
C3d | 6.6±3.8 | 33/33(100%) | 7/33(21.2%) | 0/29(0%) | 0/29(0%) | 4/33 | 4/33 | 17/33 | 8/33 |
C4d | 8.8±4.2 | 50/53(94.3%) | 5/53(9.4%) | 0/53(0%) | 0/53(0%) | 6/50 | 11/50 | 29/50 | 4/50 |
C1q | 7.6±3.6 | 76/76(100%) | 13/76(17.1%) | 0/76(0%) | 55/76(72.4%) | 13/76 | 39/76 | 20/76 | 4/76 |
MBL | 3.3±1.0 | 13/13(100%) | 13/13(100%) | 9/13(69%) | 10/13(76.9%) | 0/13 | 3/13 | 10/13 | 0/13 |
Factor B | 4.2±2.3 | 21/21(100%) | 7/21(33.3%) | 0/21(0%) | 0/21(0%) | 2/21 | 4/21 | 15/21 | 0/21 |
Properdin | 3.0±1.0 | 9/9(100%) | 3/9(33.3%) | 0/9(0%) | 0/9(0%) | 0/9 | 0/9 | 9/9 | 0/9 |
SD: standard deviation, MBL: mannose-binding lectin.