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. 2014 Mar 21;9(3):e91199. doi: 10.1371/journal.pone.0091199

Table 3. Frequencies of genotypes and alleles of microRNA (miR)-146a and Ets-1 polymorphisms in pediatric uveitis patients and controls.

SNP Genotyp Allele Pediatric uveitis (n = 520) Controls (n = 1204) χ2 p value pc value OR (95% CI)
rs2910164 GG 113(0.217) 163(0.135) 18.127 2.07×10−5 3.11×10−4 1.773 (1.359–2.313)
GC 248(0.477) 553(0.459) 0.453 0.501 NS 1.073(0.873–1.319)
CC 159(0.306) 488(0.405) 15.350 8.93×10−5 0.001 0.646(0.519–0.805)
G 474(0.456) 879(0.365) 25.080 5.50×10−7 2.75×10−6 1.457(1.257–1.688)
C 566(0.544) 1529(0.635) 25.080 5.50×10−7 2.75×10−6 0.686(0.592–0.796)
rs57095329 AA 317(0.609) 801(0.665) 4.937 0.026 NS 0.786(0.635–0.972)
AG 184(0.354) 372(0.309) 3.347 0.067 NS 1.225(0.985–1.522)
GG 19(0.037) 31(0.026) 1.502 0.220 NS 1.435(0.803–2.564)
A 818(0.787) 1974(0.820) 5.206 0.023 NS 0.810(0.676–0.971)
G 222(0.213) 434(0.180) 5.206 0.023 NS 1.234 (1.030–1.479)
rs6864584 CC 2(0.004) 5(0.004) 0.008 0.927 NS 0.926(0.179–4.788)
CT 39(0.075) 112(0.093) 1.476 0.224 NS 0.791(0.541–1.156)
TT 479(0.921) 1087(0.903) 1.466 0.226 NS 1.257(0.867–1.823)
C 43 (0.041) 122(0.051) 1.384 0.239 NS 0.808(0.566–1.153)
T 997(0.959) 2286(0.949) 1.384 0.239 NS 1.237(0.867–1.766)
rs1128334 AA 64(0.123) 145(0.120) 0.024 0.877 NS 1.025(0.749–1.403)
AG 253(0.487) 544(0.452) 1.760 0.185 NS 1.150(0.936–1.413)
GG 203(0.390) 515(0.428) 2.085 0.149 NS 0.857(0.694–1.057)
A 381(0.366) 834(0.346) 1.273 0.259 NS 1.091(0.938–1.270)
G 659(0.634) 1574(0.654) 1.273 0.259 NS 0.916(0.788–1.066)
rs10893872 CC 209(0.402) 359(0.298) 17.695 2.59×10−5 3.89×10−4 1.582(1.277–1.960)
CT 218(0.419) 620(0.515) 13.320 2.63×10−4 0.004 0.680(0.552–0.837)
TT 93(0.179) 225(0.187) 0.156 0.693 NS 0.948(0.726–1.238)
C 636(0.612) 1338(0.556) 9.270 0.002 0.01 1.259(1.085–1.460)
T 404(0.388) 1070(0.444) 9.270 0.002 0.01 0.794(0.685–0.921)

pc, Bonferroni corrected p value; OR, odds ratio; NS, not significant; SNP, single nucleotide polymorphism.