Figure 6. Arterial remodeling in cavin-1 deficient mice.

Cross-sectional area (A), wall thickness (B), arterial distensibility (C) and stress-strain relationship (D) were assessed in a pressure myograph under Ca²⁺-free conditions. Measurements of vascular wall dimensions by electron microscopy were done using perfusion fixed vessels. Representative electron micrographs are shown in (E) and measurements of media thickness and muscle cell width in arteries from six wild type (WT) and six knock out (KO) animals is shown in (F).