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. 2014 Mar 21;9(3):e92671. doi: 10.1371/journal.pone.0092671

Table 3. GRADE assessment of outcomes.

Outcome Quality assessment Quality Importance
No of studies Design Risk of bias Inconsistency Indirectness Imprecision Publication bias
VAS 5 RCT seriousa no serious inconsistency no serious indirectness no serious imprecision Undetected Moderate Critical
TT 2 RCT seriousa no serious inconsistency no serious indirectness no serious imprecision Undetected Moderate Critical
Response rate 3 RCT seriousa seriousb no serious indirectness no serious imprecision Undetected Low Critical
HTI 2 RCT seriousa seriousb no serious indirectness no serious imprecision Undetected Low Important
PFT 4 RCT seriousa no serious inconsistency no serious indirectness no serious imprecision Undetected Moderate Important
HPT 2 RCT seriousa seriousb no serious indirectness no serious imprecision Undetected Low Important
Hypoechogenicity 3 RCT seriousa no serious inconsistency no serious indirectness no serious imprecision Undetected Moderate Important

a Random sequence generation, allocation concealment and blind method were not reported in most studies.

b The heterogeneity among included studies was not neglectable.

RCT: randomization controlled trial; VAS: visual analogue score; TT: tenderness threshold; HTI: heel tenderness index; PFT: plantar fascia thickness; HPT: heel pad thickness.