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. 2014 Mar 21;9(3):e92687. doi: 10.1371/journal.pone.0092687

Figure 6. ndk-1(ok314);dyn-1(ky51) double mutants are lethal.

Figure 6

A: In the F1 progeny of ndk-1(-)/+ heterozygotes only 9.2% homozygous Pvl, Ste adults can be observed instead of the expected 25%, since 15.8% of ndk-1(ok314) homozygotes die as embryos at 25°C. At the restrictive temperature (25°C) 50% of dyn-1(ky51) single mutants die as embryos. At 25°C, in the F1 progeny of dyn-1(ky51);ndk-1(ok314)/+ animals we got decreased brood size and we did not notice any Pvl, Ste animals, suggesting that the double mutants are not viable. B: 3-fold stage homozygous ndk-1(ok314) embryo shows late embryonic lethality with persistent cell corpses. Arrows indicate apoptotic corpses.