Table 1. Characteristics of Selected Studies.
| Author | Date of study (Year) | Country | Study Design | No. of Subjects (M/F) | Mean age, % | Definition of PGD | Quality Assessment |
| King et al,7 2000 | 1990–1998 | USA | Retrospective, single-center chart review | 100(NA) | 49 | Patients with a chest x-ray film (CXR) score of ≥6 and a PaO2/FiO2 gradient of less than 200 mm Hg | Fair |
| Thabut et al,8 2002 | 1988–2000 | France | Retrospective multicenter cohort study | 257 (169/88) | 48 | The presence of reperfusion pulmonary edema with or without early hemodynamic failure. | Fair |
| Christie et al,9 2003 | 199–2000 | USA | Retrospective single-center cohort study | 252(123/129) | 49 | The presence of a diffuse alveolar infiltrate and a PaO2/FiO2 gradient of less than 200 mm Hg | Good |
| Whitson et al,10 2006 | 1992–2004 | USA | Retrospective, single-center chart review | 402 (185/217) | 50 | ISHLT PGD Grading System | Fair |
| Burton et al,11 2007 | 1999–2004 | Denmark | Retrospective | 180 (82/98) | 56 | The presence of a unilateral diffuse radiological infiltrate of the lung allograft. | Fair |
| Krenn et al,12 2007 | 2003–2006 | Austria | Prospective single-center cohort study | 150 (76/74) | 38 | ISHLT PGD Grading System | Good |
| Kuntz et al,13 2009 | 1994–2002 | USA | Secondary analysis of multicenter registry (UNOS/ISHLT) | 6984 (4315/2669) | — | A PaO2/FiO2 ratio less than 200, with evidence of radiographic infiltrates, and absence of secondary causes of allograft dysfunction. | Good |
| Felten et al, 14 2011 | 2006–2008 | France | Retrospective, multicenter cohort study | 122 (63/59) | 25 | ISHLT PGD Grading System | Good |
| Fang et al,15 2011 | 2002–2007 | USA | Prospective multicenter cohort study | 126 (60/66) | 56 | ISHLT PGD Grading System | Good |
| Allen et al,16 2012 | 2002–2007 | USA | Prospective, single-center cohort study | 28 (12/16) | 51 | ISHLT PGD Grading System | Fair |
| Shah et al,17 2012 | 2006–2008 | USA | Prospective multicenter cohort study | 108(56/52) | 37 | ISHLT PGD Grading System | Good |
| Samano et al,18 2012 | 2003–2010 | Brazil | Retrospective, single-center chart review | 78 (46/32) | 44 | ISHLT PGD Grading System | Fair |
| Diamond et al,19 2013 | 2002–2010 | USA | Prospective, multicenter cohort study (LTOG) | 1255 (211/1044) | 35 | ISHLT PGD Grading System | Good |
M, male; F, female; PGD, primary graft dysfunction; ISHLT, International Society for Heart and Lung Transplantation.