Figure 4. Small-world property of hippocampal networks at different time stages.

Normalized clustering coefficient (γ), normalized characteristic path length (λ) and small-worldness (σ) (top to bottom, respectively) of control and 3 stages of epileptiform discharges (early, middle and late stages of epileptiform discharges, abbreviated as ES, MS and LS) as a function of the cost. Lines denote the mean values and shades denote the standard errors. Difference of σ, γ and λ between early stage and middle stage are tested (*P<0.05, n = 8, paired t-test with FDR correction). Difference of σ, γ and λ between early stage and late stage are also tested (*P<0.05, n = 8, paired t-test with FDR correction).