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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Bone Miner Res. 2014 Apr;29(4):878–891. doi: 10.1002/jbmr.2105

Figure 1.

Figure 1

Diffusivity of sodium fluorescein (Stokes radius 0.45nm) and parvalbumin (Stokes radius 1.31nm) in cortical bone LCS of the 12–13 month-old CTL and perlecan-deficient (Hypo) mice. Two-way ANOVA showed that genotype (F1,92=16.4, p<0.0001) and tracer type (F1,92=25.31, p<0.0001) had significant effects on the measurements. Perlecan deficiency increased diffusion for both small and large molecules. Bars denoted with different letters are significantly different in paired comparisons (p<0.05). The sample size (the number of lacunae subjected to FRAP tests) is indicated for each study group directly under the corresponding data.