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Fiber volume fraction estimated for young adult, aged CTL and aged Hypo bones
| Fiber radius* (nm) | Young bone | Aged CTL bone | Aged Hypo bone | Relative change (Aged vs. Young) | Relative change (Hypo vs. CTL) |
|---|---|---|---|---|---|
| 0.5 | 0.4% | 0.2% | 0.1% | −50% | −50% |
| 1 | 1.7% | 1.1% | 0.6% | −35% | −45% |
| 2 | 6.1% | 4.1% | 2.7% | −33% | −34% |
| 4 | 17.2% | 13.0% | 9.5% | −24% | −27% |
Note: Fiber radius was parametrically varied from 0.5 (size of GAG), 1–2nm (size of proteoglycan core proteins), to 4nm (repeated features in endothelial glycocalyx).
