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Figure 8. Distribution of histone modifiers Ash2l, Ezh2, and Suz12 in the developing kidney. The ureteric bud, cap mesenchyme, and nascent nephrons marked by Pax2 (blue) and cap mesenchyme marked by Six2 (red) were co-stained with the H3K4 KMT Ash2l (green) and analyzed at 60× (A). The cap mesenchyme marked by Six2 (blue) and nascent nephrons marked by Lhx1 (red) were co-stained with the H3K27 KMT Ezh2 or Suz12 (green) and analyzed at 60× (B and C).
