Table 3.

Selected substrates of 11β-HSD2

Substrate	Apparent Km, μM	Species	Source	Reference Nos.
Cortisol	0.025–0.055	Human	Purified placental protein, kidney microsomes, transfected cells	90, 91
Cortisol		Mouse
Corticosterone	0.010–0.012	Human	Purified placental protein, transfected cells	90, 91
Corticosterone	0.01	Rat	Transfected cells	812
Corticosterone	100	Mouse	Mouse kidney microsomes	127
Dexamethasone	0.119	Human	Transfected cells	91
11-Dehydrodexamethasone	0.068	Human	Kidney microsomes	157

Values for transfected cells are ascertained in lysates.