Table 1.
Inositide binding domains
| Name of Domain | Lipid Species | Reference Nos. |
|---|---|---|
| Pleckstrin homology (PH) domains | PtdIns(4,5)P2 | 574, 882 |
| PtdIns4P | 381, 895 | |
| PtdIns(3,4,5)P3 | 478, 1252, 1627 | |
| PtdIns(3,4)P2 | 381, 460 | |
| FYVE domains | PtdIns3P | 1457 |
| (named after the four proteins in which they were first identified: Fab1,YOTB/ZK632, Vac1p, and EEA1) | ||
| Phox homology (PX) domains | PtdIns3P | 1721 |
| ENTH (epsin NH2-terminal homology) | PtdIns(4,5)P2 | 877 |
| ANTH (AP180 NH2-terminal homology) | PtdIns(4,5)P2 | 877 |
| FERM domains | PtdIns(4,5)P2 | 255 |
| (named after the first proteins in which they were found: 4.1-ezrin-radexin-moiesin) | ||
| PTB domain | PtdIns(4,5)P2 | 1062 |
| GLUE domain | PtdIns(3,4,5)P3 | 1416 |
| Eps15 homology (EHD) domains | PtdIns(4,5)P2, PtdIns4P | 1120 |
| BAR (Bin–Amphiphysin–Rvs) | PtdIns(4,5)P2, other lipids | 1211, 1607 |
| PDZ domain | PtdIns(4,5)P2 | 1825 |
| KA1 (kinase-associated 1) domain | Acidic phospholipids, PS | 1083 |