Table 1.

Demographic, endoscopic, and histological findings in esophagitis patients and healthy controls

Subject/Patient No.	Age, yr	Sex	BMI	Indication for Upper GI Endoscopy	Endoscopy Report	Pathology Report
Healthy subjects
1	61	M	27	Abdominal pain	Normal-looking squamous mucosa	No abnormalities
2	46	F	21	Weight loss, diarrhea	Normal-looking squamous mucosa	No abnormalities
3	23	M	26	Abdominal pain	Normal-looking squamous mucosa	No abnormalities
4	37	M	32	Vitamin B deficiency	Normal-looking squamous mucosa	No abnormalities
5	60	F	47	Abdominal pain	Normal-looking squamous mucosa	No abnormalities
6	24	F	22	Abdominal pain	Normal-looking squamous mucosa	No abnormalities
7	25	M	22	Crohn's disease	Normal-looking squamous mucosa	No abnormalities
8	46	F	21	Family history of esophageal cancer	Normal-looking squamous mucosa	No abnormalities
9	39	F	25	Severe iron deficiency anemia	Normal-looking squamous mucosa	No abnormalities
10	54	M	26	Not reported	Normal-looking squamous mucosa	No abnormalities
	41	5/5	27
Esophagitis patients
1	60	F	29	History of GERD	Irregular Z line	Mild esophagitis
2	35	F	25	History of GERD with supraesophageal symptoms	Few whitish plaques in distal esophagus	Stratified squamous esophageal mucosa with mild spongiosis and focal chronic inflammation
3	45	M	30	Odynophagia, history of GERD	Irregular Z line with short tongue of reddish colored mucosa	Mild esophagitis
4	58	M	35	History of GERD, hiatal hernia	Slightly irregular Z line, without obvious erosions	Mild esophagitis
5	30	M	29	History of GERD/heartburn	Los Angeles classification grade B erosive esophagitis	Mild Esophagitis
6	43	F	28	History of GERD	Normal-looking squamous mucosa	Stratified squamous mucosa with slight basal cell hyperplasia and slight increase in chronic inflammatory cells
7	77	M	19	History of GERD/odynophagia	Long 3-cm complex distal stricture	Ulceration and inflamed granulation
8	84	F	26	History of GERD/heartburn	Los Angeles classification grade C erosive esophagitis	Ulcerative esophagitis
9	42	M	25	History of GERD, hiatal hernia	Irregular Z line	Mild esophagitis
10	63	M	33	Screening	Irregular Z line	Mild esophagitis
11	55	F	27	Abdominal pain/recurrent dysphagia	Corrugated esophagus	Mild esophagitis
12	45	M	28	Dysphagia, history of erosive esophagitis	Los Angeles classification grade B erosive esophagitis	Mild esophagitis
13	74	M	27	History of GERD	Reddish distal mucosa	Mild esophagitis
14	77	F	27	History of GERD	Ring-type stenosis above the Z line with friable mucosa	Mild esophagitis
15	77	F	30	History of GERD	Distal esophageal stricture	Mild esophagitis
	58	8/7	28

GERD, gastroesophageal reflux disease; GI, gastrointestinal.